How Viagra acts in the body

Viagra mechanism of action involves release of natural body chemical – nitric oxide in the penis. The release of nitric oxide happens only with sexual stimulation. The nitric oxide by means of other chemical processes increases level of cyclic guanosine monophosphate (cGMP  which leads to smooth muscle relaxation and increased blood flow to the penile area. PDE 5 – phosphodiesterase type 5 – a chemical in the body that decreases cGMP in the penis, so it prevents a natural erectile process. Viagra inhibits (blocks) PDE5 selectively and thus provides loosening of the smooth muscles in the penis. Sexual stimulation is absolutely necessary for Viagra to produce its effect. Viagra is safe in recommended doses and should be taken only before sexual activity, no more than once a day (once in 24 hours). Viagra’s effects on sexual response were assessed in several clinical studies proving that the medication produced beneficial results for patients with diagnosed impotence.

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